Findings of the latest studies describes weight as an important factor in determining the risk of developing Alzheimer's disease (AD) in different genders.

According to the study published in the American Journal of Epidemiology, body mass index (BMI) and weight have dissimilar effects on the risk of developing the degenerative brain disease in men and women.
Findings revealed that the risk of developing the condition is higher among middle-aged women who are overweight, particularly those with large waists. A BMI of 30 or greater in such women is associated with a six-fold increased risk of AD.

Underweight men, however, were reported to be more vulnerable to developing Alzheimer's disease. Men with a BMI of 18.5 or less were at a five-fold risk of AD.
The study also showed a tripled risk in men who had gained a significant amount of weight between their 30s and 50s. As for women, losing weight at the same age doubled the risk of AD.

Previous studies have shown that Individuals suffering from mild cognitive impairment are more likely to develop Alzheimer's if they lose weight or are underweight.
Scientists believe fat- and appetite-regulating hormones may influence brain functions. They are optimistic that the development of an age- and gender-specific diet would help tackle the condition in high risk individuals.